NeuroCommunications

About the speaker: We focus on the characterisation of hippocampal synaptic plasticity as a learning mechanism. Two types of synaptic plasticity are primarily investigated: long-term potentiation (LTP) and long-term depression (LTD). We also study metaplasticity (as a higher order modulator of synaptic plasticity). We have a multidisciplinary approach which incorporates in vivo electrophysiology in freely moving rodents with in vitro electrophysiology using the hippocampal slice preparation, as well as behavioral analysis of learning, confocal microscopy, immunohistochemical, biochemical and molecular biological analysis. We are interested in both the physiology and pathology of learning and memory / synaptic plasticity. On a physiological level we examine how synaptic plasticity, place cells and neuronal oscillations contribute to learning and how learning drives synaptic plasticity in health and disease. Here in vivo electrophysiology and EEG analysis is combined with behavioral learning models and animal models of brain disorders.

The presentation will be hosted by Damaris Holder on behalf of the Department Cellular Neuroscience. Don’t miss your chance to talk with Prof. Manahan-Vaughan and reserve your time slot via email to the host Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!

Additionally, for Ph.D. students there is the special opportunity to join the speaker lunch at LIN at 12.30 pm. Interested researchers are very welcome to shoot the host an email Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein! to sign up for it. External Ph.D. students are also very welcome to join.